Polarimeters with Peltier temperature control

P8000-P and P8100-P

Polarimeter P8000-P with measurement tube PRG-100-EPT

Polarimeter P8000-P with measurement tube PRG-100-EPT

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Construction polarimeter glas tube PRG-100-EPT

Construction polarimeter glas tube PRG-100-EPT

Polarimeter glas tube PRG-100-ET with temperature sensor PRT-E

Polarimeter glas tube PRG-100-ET with temperature sensor PRT-E

Polarimeter glas tube PRG-100-ET with temperature sensor PRT-T

Polarimeter glas tube PRG-100-ET with temperature sensor PRT-T

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Key features
Applications
Standards
Samples
Key features

Precise temperature control using Peltier technology

High-precision measurements through temperature control without an additional device – this is what our polarimeter models P8000-P and P8100-P offer, which otherwise have the same functional scope and the same characteristics as the other devices of the P8000 series. They are recommended if the temperature of the sample is to be controlled extremely accurately within a very short period of time and with a short control cycle and independent of the outside temperature.

  • Temperature measurement directly inside the sample
  • Accurate, homogenous, fast Peltier temperature control
  • Chemical-resistant, unbreakable measurement tube
  • Highest accuracy over the entire measurement range
  • Very short measurement time of approx. 1 s
  • Measurement up to an optical density of 3.0
  • Intuitive operation via touch-screen display
  • Predefined scales (opt. rotation, spec. rotation, int. sugar scale, concentration)
  • Any number of freely definable scales with conversions based on tables or formulas
  • Chemical-resistant materials
  • Compliance with GMP/GLP, 21 CFR Part 11, Pharmakopöen (USP, BP, JP, Ph. Eur.), FDA, ISO, HACCP, OIML, ASTM, ICUMSA, NIST
Applications

Typical applications

The P8000-P polarimeters can be used for a variety of applications in the pharmaceutical, chemical, sugar, food and beverage industry, as well as for the production of flavors and fragrances.

  • Determination of the concentration of sugar as an ingredient of pharmaceutical agents
  • Purity control and content determination
  • Determination of the stereochemical composition and mutarotation
  • Characterisation of new synthetic substances
  • Purity control and concentration determination
  • Monitoring of chemical processes during the production of optically active substances
  • Characterisation tests in research laboratories
  • Reaction kinetic analyses

A comprehensive overview of typical applications with the polarimeters of the P8000 series can be found in our campus article on polarimeter applications.

Standards

Conformity with national and international standards

A big advantage of normalized measurements is the comparability of the measurement results. In many international standards and guidelines, polarimeters are recommended for specific measurement tasks as suitable measuring instruments. The requirements for the measuring devices, such as measuring accuracy and measuring temperature, are dependent on the respective measuring task and defined in each standard. We have compiled for you an overview of all known standards and guidelines, which refer to polarimetry.

  • Association of Analytical Communities (AOAC)
  • American Society for Testing and Materials (ASTM)
  • European Honey Commission (EHC)
  • International Commission for Uniform Methods of Sugar Analysis (ICUMSA)
  • European Pharmacopoeia (Ph. Eur.)
  • United States Pharmacopoeia (USP)

A PDF overview of these standards is available for download at the following link:

Polarimeter Standards (PDF, 110 KB)

Any questions?
Feel free to contact us, we will assist you in choosing the right polarimeter for you.

Samples

Measuring optically active substances

Many biologically important substances such as amino acids, sugars, enzymes or receptors are chiral compounds and have the ability to rotate linear-polarized light. Almost all natural amino acids rotate linearly polarized light to the left, whereas natural sugars (eg D-glucose) almost exclusively turn right. These substances have the same physical properties as density, melting point, boiling point or IR spectrum except for their optical activity. Depending on the direction of rotation, chiral substances can have very different physiological effects on living organisms. Therefore, measurement of optical purity with a polarimeter is an important quality criterion in the production of chiral drugs in the pharmaceutical industry. Due to the proportionality of the rotation value α and the concentration c, it is possible to carry out quantitative content determination of sugar solutions in the sugar processing industry (saccharimetry).

A high-quality optics, intelligent evaluation logarithms, LEDs with different wavelengths and a consistent measuring accuracy over the entire measuring range are available for the quantification and characterization of all optically active substances.

In the following table we have compiled an overview of frequent samples from our customers. Most samples were measured at standard measurement conditions (20 ° C, λ = 589 nm). Deviations are indicated. The measurements given are not specifications.

The PDF overview of these samples is available for download at the following link:

Polarimeter samples and their optical rotation (PDF, 138 KB)

Any questions?
Get in contact with us, we will assist you in choosing a suitable polarimeter.

Model specifications

 P8000-PP8100-P
SCALESOptical rotation [°]
Int. sugar scale [°Z]
Concentration [g/100 ml]
Spec. rotation
User-defined
MEASUREMENT RANGES±90°
±259 °Z
0–99.9 g/100 ml
ACCURACY±0.003°
±0.01 °Z
±0.5 g/100 ml
±0.002°
±0.01 °Z
±0.5 g/100 ml
RESOLUTION0.001°
0.01 °Z
0.1 g/100 ml
TEMPERATURE
TEMPERATURE MEASUREMENTWith measurement tube PRG-100-EPT
TEMPERATURE MEASUREMENT RANGE0–99.9 °C
TEMPERATURE MEASUREMENT RESOLUTION0.1 °C
TEMPERATURE MEASUREMENT ACCURACY±0.2 °C
TEMPERATURE CONTROLWith measurement tube PRG-100-EPT with 3 integrated Peltier elements
TEMPERATURE CONTROL RANGE15–40 °C
TEMPERATURE CONTROL ACCURACY±0.2 °C
OTHER SPECIFICATIONS
MEASUREMENT PERIOD ±90°Approx. 1 s
LIGHT SOURCE 1 LED with filter
WAVELENGTH589 nm

Technical data polarimeters (PDF, 1000 KB)

A strong performance package

The A.KRÜSS polarimeters are the fastest in the world thanks to the patented measuring method. They achieve high measuring accuracies, have an intuitive user interface, complete measured value documentation and compliance with global standards. Thanks to the many functionalities, the P8000 models are a worthwhile investment

 

Intuitive operation

  • State-of-the-art touch-screen display
  • [L: Uniform operation of all A.KRÜSS laboratory devices]
  • Secondary scale for displaying a second measured value
  • Freely assignable shortcut keys for the most important functions
  • Easy, menu-driven adjustment
  • A selection of six languages (de, en, es, fr, it, pt)
 

Fast reliable measurement

  • Measurement up to an optical density of 3.0
  • Very short measurement time of approx. 1 s – the fastest polarimeters in the world!
  • Measurement with manual measurement time input or optimised measurement time thanks to automatic stability recognition
  • Reliable temperature compensation
  • Highest accuracy over the entire measurement range
 

Easy filling and cleaning

  • Suitable tubes for any type of sample
  • Manual, semi-automatic or fully automatic sample supply
  • Chemical-resistant materials
  • Freely configurable cleaning procedures
  • Semi-automatic or fully automatic drying
 

Unlimited number of methods

  • Create any number of methods and analyse each sample using the desired parameters
  • Method parameters: scales, temperature, temperature compensation, sample supply, wavelength, tube length, limit values, comment and many more
  • Measurement modes: single, continuous or interval measurement
  • Predefined scales for optical rotation, specific rotation, sugar content and concentration
  • Any number of freely definable scales with conversions based on tables or formulas
 

Inteligent unser administration

  • Can be activated or deactivated depending on the requirements
  • Two authorisation levels
  • Optional setup of user profiles
  • Customised settings for different users or work groups
 

Complete documentation of measured values

  • Complete recording of all measured data as well as system and method settings in a tamper-proof data storage
  • Documentation of all measured values of the last 999 measurements with consecutive numbering
 

Flexible data export

  • Print-out on serial ASCII printer
  • Print-out on network printer in PDF or GS format
  • Print-out as PDF on USB flash drive or to network share
  • Export in HTML or CSV format on USB flash drive or to network share
  • Can be connected to a keyboard, mouse, barcode scanner or external PC in order to use the KrüssLab software
  • Easy integration into existing networks (DHCP Client) or a LIMS
 

Polarimeter solutions for any need

  • P8000/P8100 without temperature control
  • P8000-T/P8100-T with water bath temperature control
  • P8000-P/P8100-P with Peltier temperature control
  • P8000-TF/P8100-TF with water bath temperature control and flow-through function
 

Compliance with global standards

  • GMP/GLP
  • 21 CFR Part 11
  • Pharmacopoeias (USP, BP, JP, Ph. Eur.)
  • FDA, ISO, HACCP, OIML, ASTM, ICUMSA, NIST
 

Polarimeter glass tube with integrated Peltier temperature control

The PRG-100-EPT is a directly temperature-controlled measurement tube for our polarimeters P8000-P and P8100-P which allows high-precision measure ments without the use of an additional external device. Three Peltier elements ensure an accurate, fast temperature control in the range between 15 and 40 °C.

PRG-100-EPT
 

Campus

Automation with polarimeters

Maximum efficiency and increased time savings through automation options - with our polarimeters P8000-TF and P8100-TF with their temperature-controllable measuring tubes, the entire measuring process can be carried out semi-automatically or fully automatically and without manual intervention, from sample supply to cleaning to drying.

More about automation
 

Service

Our service is unbeatable

As a customer you are at the center of our service, and for your satisfaction we give our best every day. Quality is always our top priority. Whether commissioning, calibration, maintenance or repair: with our certified service and repair services, you can rely on the first-class expertise of our specialists.

Our certified services
 

Any Questions?

We will be glad to help.

+49 40 514 317-0

sales@kruess.com

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